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Research Scientist
The Research Scientist will support molecular breeding deployment in North America-East South region, including hands on genetic analysis, software support, training of new tools, field experimentations, and appropriate precision phenotyping. Duties/Responsibilities Collaborate with in-house research efforts to identify and monitor germplasm diversity using molecular tools and its application to hybrid advancement.

Work with other corn breeders to develop strategies to identify the underlying genetic factors responsible for traits important to the breeding program.

Mine and share Quantitative Trait Loci (QTL) information across the breeding organization. Educational Qualifications Desired PhD in plant breeding or plant genetics, with an emphasis in the areas of genetics and molecular genetics, or related field and minimum of 2 to 4 years of related experience or equivalent amounts of relevant education and experience preferred. Masters degree in an agriculture or scientific field and minimum of 6 to 8 years of industry related experience required. Post doctoral experience may serve as experience. Competencies and Experience Desired Comprehensive knowledge and applied research experience in plant genetics, plant breeding.
Strong communication skills and a proven ability to work well in a team environment.
Experience or familiarity with quantitative/population genetics and of meta analysis methods.
Publ.Date : Tue, 31 Aug 2010 09:30:53 +0100

Research Scientist
This is a new software developer/statistical scientist position in the Genetic Discovery group. This is an enthusiastic group of geneticists and molecular biologists working at the forefront of plant agriculture research and development. The advent of high-throughput technologies for DNA sequencing, and plant phenotyping results in the generation of large, high-dimensional datasets, and creates new challenges in data analysis for genetic and genomic studies. Specific areas for software development and statistical work include next-generation sequencing, genome-wide association studies, gene expression microarrays, quantitative genetics, and multivariate statistical analysis. Duties/Responsibilities The scientist will provide software development or statistical support for marker-based studies in plant genetics and genomics. Depending on expertise the scientist will be engaged in the following areas. The scientist will develop server-based data analysis applications within our web-based lead tracking environment. The scientist will assist with experiment design, data management, and statistical inference. The scientist will optimize or develop data analysis methodology. The scientist will collaborate with various scientists in Genetic Discovery, Bioinformatics, IT, and Agronomic Trait Development. Educational Qualifications Desired PhD in biological science, applied mathematics, statistics, engineering or related discipline and minimum of 2 to 4 years of direct biological research experience is preferred. Masters degree in biological science, applied mathematics, engineering or related discipline and minimum of 6 to 8 years of direct biological research experience required, or equivalent amounts of relevant education and experience. Post doctoral experience or other relevant software development education and experience will also be considered. Competencies and Experience Desired For software development, the position requires expertise in object oriented programming, relational databases, and server-based web application development. Requires knowledge of Java and perl.

For statistical work the position requires broad knowledge of statistical genetics, multivariate statistical analysis, linear models, multiple comparison correction methods, and bootstrap methods.
Requires expertise in the multivariate analysis of large datasets for SNPs, genome-wide association studies, gene expression, and the use of related statistics packages and data visualization tools.
The general requirements are as follows.

Requires expertise in computational methods, a programming language such as Java, or a high level scripting language such as R, perl or Groovy, on Windows and linux systems.
Requires expertise in the design and implementation of software for handling large datasets and data analysis, and the use of relational databases.

Familiarity with quantitative analysis of high-throughput sequence data would be an advantage.
Strong communication and interpersonal skills are required.
Publ.Date : Mon, 16 Aug 2010 11:08:50 +0100

Research Scientist - Corn
This position is located in Woodstock, Ontario Canada.

Job Description: The Research Scientist will be responsible for planning and conducting a comprehensive maize breeding program encompassing inbred development through hybrid commercialization adapted to 85-90 CRM maturity areas of northeastern North America. This position will work with numerous other Maize Product Development Scientists to utilize enabling breeding technologies to maximize genetic gain in their breeding program. They will leverage quantitative and molecular genetic knowledge to improve maize inbreds, while developing and testing experimental hybrids. Technical abilities need to be supported with strong communication, team building and leadership skills. The scientist will provide leadership to research center staff and activities.

Duties/Responsibilities: Directly responsible for planning and conducting a comprehensive maize breeding program for 85-90 CRM. Lead establishment of product development plans for molecular breeding projects and create product opportunities working collaboratively with other scientists to effectively share ideas, discuss approaches, implement plans and summarize results.

Leverage enabling breeding technologies to drive and accelerate product development improvements including but not limited to breeding and selection of doubled haploid lines while utilizing genotypic and phenotypic data to identify improved inbreds and hybrids.

Design experiments to characterize/screen germplasm for complex traits. Work with collaborators to design experiments that improve understanding of the genetic basis of quantitative traits.

Contribute to all leadership aspects of research center activities and effectively communicate with other scientists as necessary to ensure success. Lead technical support staff to effectively oversee the research center including recruiting, hiring, and managing effective performance. Support the Sales team by providing input on new products and by providing technology updates and discussions at Sales training sessions and at grower meetings.

Educational Qualifications Desired: Ph.D. in plant breeding or plant genetics, with an emphasis in the areas of statistics, quantitative and molecular genetics. Three years or more of field research experience is highly preferred.

Competencies and Experience Desired: Comprehensive knowledge and applied research experience in plant genetics and plant breeding with a background in the use of molecular markers and strong aptitude for managing large data sets.

Strong verbal and written communication skills and a proven ability to work well in a team environment effectively developing internal and external working relationships with a diverse group of people.

Strong self-motivation with leadership capabilities to motivate others, initiate projects, make decisions and solve problems.

Understanding of small plot research techniques leading to high quality data is essential. Ability to work outside in varying environmental and ergonomic conditions with a willingness to work additional hours/weekends during peak periods.

Excellent computer, data management, statistical analysis, and data presentation skills are essential.

Understanding of product needs for North American maize markets.

Valid driver’s license or the ability to obtain.

Occasional overnight travel is required.

Apply online by clicking Apply Now below. Refer to job #12255BR under the International Job openings. Apply by September 03, 2010.
Publ.Date : Tue, 17 Aug 2010 16:08:04 +0100

Product Development Scientist
Work in a team of agricultural research scientists with the goals of developing elite germplasm to create improved inbreds and superior, market leading hybrids for Western Europe by increasing the rate of genetic gain, increasing harvestable yield, improving key agronomic traits, and integrating value-enhancing traits into Pioneer germplasm. Duties/Responsibilities Position will be responsible for planning, leading and conducting a comprehensive maize breeding program for the development of inbreds and hybrids with high level of performance and agronomic stability for Western Europe. The position will be based in Epuiseau, France. The position will require effective teamwork in a complex, multidisciplinary setting across product development, product characterization and commercialization, and other groups within Crop Genetics Research & Development. Technical abilities need to be supported with strong communication, team building, and leadership skills. Educational Qualifications Desired Ph.D., or equivalent, in plant breeding, genetics, or related field with a strong background in molecular and whole plant genetics and supporting sciences. Competencies and Experience Desired Must have a strong background in genetics and demonstrated ability to apply new technology. Proven ability to work well in diverse scientific and professional settings. Ability to show leadership and be successful in a team environment. Demonstrated ability to develop effective relationships with others, to understand differing perspectives and objectives, and to recognize and effectively balance differing perspectives and agendas. At least 3 years plant breeding experience in the seed industry or university setting. Very good written and oral communications skills in English essential, knowledge of French desired.
Publ.Date : Mon, 16 Aug 2010 11:12:15 +0100

Strategic Trait Cotton Breeder - Scott MS (0027A)
Strategic Trait Cotton Breeder - Scott MS - 0027A Description Monsanto is seeking a highly motivated individual to become an integral member of a multidisciplinary Global Cotton Breeding team. The Strategic Trait Breeder will have responsibility for managing the Strategic Trait Breeding program at Scott, MS and will involve the identification and integration of key breeding traits and transgenic traits into pipeline level germplasm while maintaining maximum genetic gain. Key responsibilities are: to ensure that the research program follows all ESH procedures for safe operation; assist in trait discovery efforts; germplasm evaluation; and the development of genetic populations for use in marker-trait association and for genetic advancement to the pipeline stage. The incumbent will be a key member of the cotton breeding team. The Strategic Trait Breeder will directly interact with Cotton Breeding team members involved with strategic trait breeding, greenhouse and nursery operations, testing operations, commercial breeding and international breeding. The incumbent will also coordinate activities with other groups, such as high throughput DNA analysis labs, quantitative genetics, breeding technology, and biotechnology. This role offers the opportunity to work with the world's largest global pool of germplasm and traits to create the next generation of commercial cotton products. Responsibilities: Assist in Discovery efforts which will include population development, phenotyping, marker-trait association, fine mapping and validation Evaluate germplasm for presence of key traits Identify appropriate germplasm sources breeding Develop breeding populations for the integration of traits into pipeline germplasm Enable and validate DNA marker haplotypes that can be utilized in broad scale marker assisted selection for the strategic traits Coordinate with commercial breeders the advancement of lines possessing key traits Qualifications Required Skills/Experience: PhD in Plant Breeding, Genetics, or related field Ability to successfully manage people and to lead and function in a multidisciplinary team. Sound knowledge of plant breeding principles and procedures Basic understanding of genetics, molecular biology and molecular breeding methods and techniques. Effective verbal and written communication skills Computer skills related to data acquisition and analysis. Working knowledge of Outlook, Excel, PowerPoint, and Word Preferred Skills/Experience: Three or more years of post graduate experience Experience in breeding and genetics of cotton or another self-pollinated crop Demonstrated experience in marker assisted selection Job Research & Development Primary Location North America-USA-Mississippi-Scott Organization Global Cotton Breeding_51113280 Schedule Full-time
Publ.Date : Thu, 02 Sep 2010 08:04:08 +0100

Statistical Genetics Analyst - Deciphering Developmental Disorders – Ref: 80721
The Wellcome Trust Sanger Institute is a world leader in genomic research, with an expanding scientific programme dedicated to understanding gene function in health & disease.

The Deciphering Developmental Disorders (DDD) project is a new initiative co-funded by the Wellcome Trust and the Department of Health to utilise the latest techniques in genomics to identify the genetic causes of developmental disorders.

Developmental disorders are conditions that are the result of problems during the development of the body or the brain and are apparent in children from shortly after birth. Currently, in the majority of cases we do not understand why the disorder has happened. However, we know that a significant proportion of developmental disorders are due to genetic factors. This project will study families with at least one individual affected with a developmental disorder recruited within the 23 Regional Genetics Services of the NHS. We will use very high-resolution genomic techniques including DNA microarrays, genotyping and next generation DNA sequencing to identify mutations that might explain the developmental disorder and so provide diagnoses for families and increase our knowledge of gene function in health and disease.

We are looking for a talented individual to develop, implement and apply statistical genetics methods and analyses in the context of large-scale studies of rare human disease, particularly the analysis of DDD project data.

Essential Skills
The successful applicant is likely have a PhD or an equivalent level of experience in Statistical Genetics, or a closely related field and a strong background in computer programming. Previous experience of the analysis of genome-wide associations, imputation of genotyping data or next generation sequencing would be a distinct advantage.

Other information
There is funding available for this position until 30th September 2015.

Benefits
The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website https://jobs.sanger.ac.uk,

To submit your CV and apply for this job please go to https://jobs.sanger.ac.uk, to register and apply on line.]

Salary range £27316 to £37690 dependent on experience.

Closing date: 23rd September 2010
Publ.Date : Wed, 25 Aug 2010 09:13:49 +0100

Postdoctoral Fellow - Mouse Behavioural Genetics - Ref: 80702
Salary range £28000 to £34433 dependent on experience.

Closing Date: 16th September 2010.

The Wellcome Trust Sanger Institute is a world leader in genomic research, with an expanding scientific programme dedicated to understanding gene function in health & disease.

We are seeking a Postdoctoral Fellow with a background in mouse genetics or behavioural neuroscience to study the olfactory mechanisms of instinct in mammals.

The successful applicant will join Darren Logan's group at the Wellcome Trust Sanger Institute. The position will involve a combination of genetic engineering technologies, behavioural analysis, genome informatics and neural activation studies in mice, to understand how pheromones and their receptors together instruct social interaction. The group is interested in a number of instinctive, olfactory-mediated behaviours including aggression, fear, sexual attraction and feeding.

The Sanger Institute is a world leader in large-scale genome sequencing, informatics and the production of animal models to study gene function; providing the successful candidate with excellent resources and a stimulating research environment. There is a commitment to personal and professional development in the group, and the successful applicant will be encouraged to develop their own ideas, drive their research project and establish a strong academic profile.

Essential Skills:
We are seeking a highly motivated and talented postdoctoral researcher with a background in sensory biology, neuroscience, behaviour, or another relevant discipline, who may have a proven track record in genetic research or who has demonstrated exceptional potential during a recently completed PhD. Molecular biology experience and a willingness to work with animals is essential.

Ideal Skills:
The ideal candidate will have a strong record of published work and be comfortable presenting their research to diverse audiences. Experience in any of the following techniques would be desirable: DNA sequence or genomic analysis; informatics; confocal microscopy; immunohistochemistry; construction of gene targeting vectors; ES cell culture; primary neuronal cell culture; calcium imaging; expression of recombinant proteins; analysis of animal behaviour.

Other information:
Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training. The post is a three year fixed-term contract. Successful applicants who have submitted their PhD thesis and are awaiting their PhD award to be confirmed will be placed on a transitional pay point, currently £25,845. On confirmation applicants will be moved on to the pay scale above.

Informal enquiries to Darren Logan (dl5@sanger.ac.uk)

Benefits:
The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website https://jobs.sanger.ac.uk,

To submit your CV and apply for this job please go to https://jobs.snger.ac.uk, to register and apply on line.
Publ.Date : Fri, 20 Aug 2010 09:24:02 +0100

Statistical Geneticist (Scientist I or II)
Statistical Geneticist (Scientist I or II) City: Raleigh-Durham
Job ID: 13A9188C-AD27-43C6-A847-4AA4ADD4F385 Role Purpose/Accountabilities
The primary purpose of the Statistical Geneticist is to develop and implement statistical methods for linkage and association analysis to detect and characterize the genetic factors underlying complex traits (eg. yield, stress tolerance, etc.). In a highly team-oriented environment the Scientist will support Native Trait Project Leaders and implement emerging statistical tools and methodologies, and will enable the generation and distribution of readily applicable trait-specific genetic information culminating in Native Trait enhanced products.

Accountabilities
. The scientist will be responsible to apply advanced statistical methods, computer science skills and bioinformatics principles to analyze genotypic and phenotypic data from a wide variety of genetics studies, including large-scale whole genome association, transmission disequilibrium, linkage studies and population genetic studies.
. The successful candidate will use this experience to develop analysis workflows and help in the automation of these workflows.
. The candidate will also be responsible for developing statistical methodology to leverage the use of existing breeding populations for developing marker: trait associations.
. In order to accurately identify the required novel analytical approaches, this individual will be trained on most commercially available software packages in the field of statistical genetics and will work closely with the computational biology group to fully understand the different algorithm details, advantages and limitations.

Knowledge, Skills & Experience
Knowledge, experience & capabilities
. Ph.D. in Statistical Genetics / Mathematics / Bioinformatics / Computer Science
. Experience in analysis of genetic and phenotypic data, including whole-genome mapping studies by association and linkage, haplotype analysis, population genetics, and admixture analysis, etc.
. Computer skills: High degree of proficiency with: OS: Linux / Unix, Windows ; Programming: Perl, C++
. Statistical software: R / S-Plus / SAS / JMP / ASREML
. Previous experience with mixed-model and/or Bayesian methods for genetic evaluation.
. Ability to work as part of a high performance multi-disciplinary team.
. Ability to handle several projects simultaneously.
. Excellent verbal and written communication skills
. Strong initiative and demonstrated ability to take ownership of and provide solutions to challenging problems

Critical knowledge
. Expertise in statistical genetics
. A thorough knowledge of plant or animal breeding theory and Mendelian genetics (experimental designs, descriptive and test statistics, genetic gain theory, genetic models, etc.).

Critical experience
. Demonstrated experience in specific projects and success in the area or a related area.

Critical technical, professional and personal capabilities
. Excellent organization, communication and analytical skills. Excellent interpersonal skills, especially those required to successfully function as part of cross-functional and cross-cultural teams. Ability to understand and communicate complex instructions. Capacity to innovate in a focused and product-oriented manner.

Critical leadership capabilities
. Decisive
. Trusted
. Customer-Focused
. Results-Oriented
. Communicative
. Team-Oriented
. Innovative
. Initiative
. Analytical thinking

Critical Success Factors & Key Challenges
. Excellent organization, communication and analytical skills. Excellent interpersonal skills, especially those required to successfully function as part of cross-functional and cross-cultural teams. Ability to understand and communicate complex instructions. Capacity to innovate in a focused and product-oriented manner.

Additional Information
. A minimum of 2 years in current position is required (requirement for internal applicants only)
. All applicants must be eligible to work in the US.
. Some travel by car and plane.
. Periods of intense work at critical times of the projects
. Indoor - extensive work at a computer for long periods of time.
Publ.Date : Wed, 18 Aug 2010 10:20:40 +0100

Senior Research Associate
Provide computer and software support for researchers in the Maize Product Development area. The Senior Research Associate will work with project leaders to support data management and software needs of research clients. Duties/Responsibilities The successful applicant will be part of a team providing software support for researchers working in Maize Product development. This position will serve as a primary support contact for the North American Hybrid Characterization Process. Successful applicant will also be responsible for leading new projects focused towards Maize product development and advancement areas. The Senior Research Associate will be expected to help researchers manage information effectively by analyzing needs, providing ad-hoc reporting, software troubleshooting and validation, proactively communicating solutions, and providing documentation, training and support in the use of software and database applications. Educational Qualifications Desired Bachelor's degree in plant breeding/genetics, molecular genetics, plant biology, agronomy or related scientific field and minimum of 2 to 4 years of industry related experience is required, or equivalent amount of relevant education and experience. Masters degree in plant breeding/genetics, molecular genetics, plant biology, agronomy or related scientific field and 0 to 2 years of industry related experience is preferred. Competencies and Experience Desired Educational background and work experience in plant breeding, genetics, molecular biology, and statistics.
Familiarity with personal computer software, client-server technology, and their application to plant breeding and genetics.
Demonstrated advanced application of Excel for processing, analysis and presentation of research data.
Excellent written and oral communication skills and ability to communicate complex information in a clear and concise manner.
Demonstrated ability to effectively manage priorities in multi-task work environment with attention to detail.
Experience in Process Mapping and Project management a plus.
Basic understanding of relational databases and ability to extract and summarize large amounts of data.
Demonstrated ability to work cooperatively in a team environment.
Computer user education or similar training/teaching experience.
Knowledge and skill in DNA marker technologies and their application to applied plant breeding programs is an advantage.
Some overnight travel will be required.
Publ.Date : Mon, 16 Aug 2010 08:31:14 +0100

Tenure Track Faculty Positions
The Department of Human Genetics at the University of Michigan Medical School seeks M.D., Ph.D., and M.D./Ph.D. scientists with an exceptional record of research accomplishment to join a growing community of faculty with active research programs in molecular, developmental, population, and statistical genetics. Preference will be given to applicants conducting cutting-edge research in genetics, genomics, or epigenetics using patients, populations, and/or model organisms.

To apply please submit a C.V., research description, and three letters of recommendation to the University of Michigan website behind the "Apply Now" button. Applications will be considered for tenure-track positions at the level of Assistant, Associate or Full Professor. Preference will be given to completed applications received on or before October 15, 2010.

The Department of Human Genetics offers highly competitive start-up packages. The University of Michigan is an Affirmative Action/Equal Opportunity Employer.

Correspondence may be addressed to:

John V. Moran, Ph.D., Chair of Faculty Search Committee
Investigator, Howard Hughes Medical Institute
Professor, Departments of Human Genetics and Internal Medicine
Phone: 734-615-0456
Lab: 734-615-0457

Publ.Date : Wed, 01 Sep 2010 16:06:36 +0100

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